| Csapat | Gyártó | Motorkerékpár | Versenyzők |
|---|---|---|---|
| Aprilia Racing | Aprilia | RS-GP | Jorge Martín, Lorenzo Savadori, Marco Bezzecchi |
| Ducati Lenovo Team | Ducati | Desmosedici GP25 | Marc Márquez, Francesco Bagnaia |
| Monster Energy Yamaha MotoGP Team | Yamaha | YZR-M1 | Fabio Quartararo, Alex Rins |
| Pertamina Enduro Yamaha Racing | Ducati | Desmosedici GP24/25 | Fabio Di Giannantonio, Franco Morbidelli |
| Castrol Honda LCR | Honda | RC213V | Johann Zarco, Somkiat Chantra |
| Honda HRC Castrol | Honda | RC213V | Luca Marini, Joan Mir |
| Red Bull KTM Factory Racing | KTM | RC16 | Brad Binder, Pedro Acosta |
| Prima Pramac Yamaha MotoGP | Yamaha | YZR-M1 | Miguel Oliveira, Jack Miller |
| BK8 Gresini Racing MotoGP | Ducati | Desmosedici GP24 | Fermin Aldeguer, Álex Márquez |